Can enzymes change the blood type of a donated kidney?

The answer

In 2025, researchers demonstrated that enzymes can convert a donated kidney from blood type A to universal type O, potentially eliminating one of the biggest barriers in organ transplantation - blood type incompatibility. The enzymes strip away the A-type sugar antigens from the kidney's blood vessels, making it compatible with any recipient regardless of blood type. This breakthrough could dramatically expand the pool of available organs, since blood type matching currently prevents many otherwise viable transplants. About 17 people die every day in the United States waiting for organ transplants.